Cellular Adhesion & Cytomechanics

JPK's CellHesion® products quantify single cell-cell and cell-surface interactions under physiological conditions. This ground-breaking technique, known as single cell force spectroscopy (SCFS), measures the interaction forces between a living cell bound to a cantilever and a target cell, functionalised substrate or biomaterial. In parallel, cytomechanical characteristics including stiffness and elasticity can be determined.

Uniquely, specific and non-specific adhesion events are differentiated. The roles of cell adhesion molecules, extracellular matrix proteins, antibodies and drugs can be quantified to characterize processes from single integrin binding through to membrane tether extraction. JPK's instruments deliver new insights in developmental biology, cancer biology, immunology and biocompatibility.

JPK provides both a stand-alone platform to add to your inverted optical or confocal microscope and an accessory module for JPK's powerful NanoWizard® Atomic Force Microscope (AFM). Easy to use acquisition software combined with automated batch analysis of results accelerates research and reduces your time to publication.

• CellHesion® 200  - a dedicated platform for cell adhesion and cytomechanics studies

• CellHesion® Module - accessory for the NanoWizard®II AFM combines cell adhesion and mechanics with AFM imaging techniques