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Agilent Technologies, Inc.

Seahorse XF Plasma Membrane Permeabilizer

The Seahorse XF Plasma Membrane Permeabilizer (PMP) is a proprietary reagent that permeabilizes intact cells in culture, selectively targeting the cellular plasma membrane while leaving the mitochondrial membrane intact, allowing for detailed characterization of key components in mitochondrial function including transporters, enzymes, and electron transport chain complexes. This reagent can also be used in other assays involving cell permeabilization, including perforated patch, dye loading and muscle physiology.

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Features

  • PMP targets cellular plasma membrane selectively and is superior to other detergent-based permeabilizers.
  • It allows to study mitochondrial function without the need to isolate mitochondria.
  • Minimal optimization is required – 1.0 nM works for most cell types.
  • The product provides consistent results in every assay.
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Resources

Downloads

Download the Agilent Seahorse XF Assay Kits & Reagents Overview
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Download the new Media Selection Guide
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Download the Seahorse Plastics Brochure
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Download the Seahorse XF Instrument Selection Guide
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Agilent Technologies, Inc.

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