S2 Genomics
Singulator 100 – Single cells or nuclei from solid tissues in minutes
Solid Tissue Dissociation. Automated.
The bench-top Singulator System and its single-use cartridges enable reproducible, rapid and hands-off tissue dissociations into single-cell or nuclei suspensions. Its ability to perform cold dissociation minimizes the expression of stress-related genes in cells and helps preserve RNA quality in nuclei. Researchers can now easily obtain suspensions of nuclei or high-viability cells for a wide range of single-cell analyses.
Say Goodbye To Manual Tissue Dissociation.
Minimal Variability. Multiple Applications.
Ideal for genomics, cell biology and other ‘omics applications, including scRNA-Seq, snRNA-Seq, ATAC-Seq, CITE-Seq, FACS, and immuno-oncology. S2 Genomics provides a selection of pre-set protocols and pre-formulated reagents for cell isolations for an expanding set of mouse, rat, and human tissues, including tumors.
Click below in order to see the wide range of tissues and organisms demonstrated on the Singulator 100 System.
Tissue Types
About the Technology
Sample to Genomics Solutions
S2 Genomics is developing integrated sample preparation systems for processing tissues into genomic samples for single-cell genomics and cell biology studies.
The Singulator™ 100 enables rapid and hands-off tissue dissociations, making it easy for researchers to reproducibly prepare suspensions of nuclei or highly viable cells from small samples in high yield, for a wide range of single-cell analyses.
The Singulator 100 overcomes the challenges with manual tissue preparation methods by producing consistent cell or nuclei isolations from a variety of solid tissue samples, reducing hours of hands-on processing to minutes.
Spatial Sequencing™
S2 is developing single cell spatial sequencing technology that will capture the spatial location, i.e., 3-dimensional coordinates, of single cells in tissue for NGS readout.
Spatial sequencing™ will be a key to understanding
- Tissue micro environments and how the diversity of heterogeneous cells affects human health, including cancer formation and progression
- How the microbiol interacts with the host
- Cell and tissue response to stimuli including therapeutic agents,
- How organism and tissues develop, organize, function, and regenerate in all multi cellular organisms
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