Agilent Seahorse XF Technology – Measure what’s important to your cells

Using Agilent Seahorse XF Analyzers, scientists are continuing to obtain powerful functional data from live cells, in real time, gaining a greater understanding of cell metabolism. With this event we aim to provide an overview of the broad range of applications and to highlight the huge impact functional metabolism has.

Essentials for Scientists in Academia and Industry

Historically, drug discovery is a lengthy, expensive, difficult, and inefficient process. But there is light at the end of the tunnel. We are inviting experts from academia and industry in order to elucidate the drug discovery process from basic research and target identification, including further characterization and development. For every step we provide state-of-the-art technology that can significantly improve your results.

This webinar discusses how autophagy-dependent metabolic reprogramming may rescue the antiviral potency of anti-HIV-1 T-cells in subjects under antiretroviral therapy (ART). Although conventional ART manages to suppress HIV-1 infection’s progression, it does not restore a proper T-cell’s immunity. Here, we propose that autophagy is a pivotal key process to mount an effective T-cell responses and metabolic fitness by providing diverse carbon sources within a hostile environment during persistent HIV-1 infection.

Tune in to learn more about how:

• Autophagy confers differential metabolic reprogramming in a T-cell subset-dependent manner.
• Autophagy is regulated through IL-21 and AMPK signaling in T-cells, providing the proper mitochondrial bioenergetics requirement.
• Autophagy is a valuable therapeutic tool to enhance T-cells antiviral immunity.

Speaker:
Hamza Loucif
PhD Candidate 
INRS-Centre Armand-Frappier Santé Biotechnologie, Laval, Quebec, Canada

Narrowing the in vitro – in vivo divide. The importance of oxygen (measurements) in the tumor micro-environment (Introductory presentation by Daniel Gebhard)

Identification of metabolic mechanisms driving cancer cell radiation resistance and associated therapeutic opportunities (Keynote by Dr. Johann Matschke)

Learning points:

• Cell metabolism affects radiotherapy response
• Hypoxia alters cellular metabolism and radiation response
• Metabolic adaptation creates targetable vulnerabilities
• Radiation treatment for context specific synthetic lethality

Speakers:
Dr. Daniel Gebhard
Product Specialist Cell Analysis, Agilent Technologies

Dr. Johann Matschke
Group Leader Metabolism and Radiation Response
Institute of Cell Biology (Tumor Research), University Hospital Essen

Join a virtual event with Mission Bio to hear the highlights of the Tapestri Platform expansion and learn how you can do more single cell in less time with lower sample input to enable new avenues for your research that were previously impossible.

We'll be joined by Dr. Koichi Takahashi of MD Anderson Cancer Center who will share his work in leukemia research using novel multi-omics applications.

Join this webinar to learn more about the alteration of host gene expression as a result of COVID-19 infection, and novel laboratory techniques designed to evaluate this at a single-cell resolution.

Speakers:
Bruce Wang
Assistant Professor in Residence, Div. of Gastroenterology, UCSF

Please stop by at our booth and we will be happy to discuss your specific research needs.

Plenary speakers of the meeting will be:

• Prof. Ralf Brandes (Vascular Research Centre. Frankfurt am Mainz, DE)
• Prof. Miriam Stoeber (University of Geneva, CH)

Another highlight is the awarding of the Young Investigator Award by the "Stiftung Physiology" (former Oetliker Foundation) to the best posters & best talks!

The conference is planned as an on-site meeting, with all necessary measures to ensure a safe meeting.

ILMAC is Switzerland’s leading trade fair for experts from more than 20 different branches of industry. Roughly half the visitors to ILMAC come from the pharmaceutical and chemical industries. In addition, mechanical, plant and apparatus engineering professionals, and also laboratory and biotechnology experts similarly use ILMAC as a contact platform.

Stop by at our Booth B163