In this webinar, Assaf Magen of the Precision Immunology Institute at Mount Sinai Icahn School of Medicine will review the recent neoadjuvant clinical trial of PD-1 blockade in early-stage hepatocellular carcinoma (HCC) patients, in which the team observed a 30 percent pathological response rate, prompting a detailed investigation into the cellular and molecular pathways that promote an effective anti-tumor immune response. Magen and team focused on T-cell-rich lesions (in contrast to T-cell-low or excluded tumors) because, despite no apparent defects in T-cell priming and recruitment to tumors, a large subset of T-cell-rich lesions still failed to respond to checkpoint blockade.

In this webinar, Magen will discuss:

• How mregDC/T-helper niches enable local reactivation of CD8 T cells upon PD-1 blockade.
• Correlations and mechanisms of response to ICB in early-stage HCC.
• Single-cell molecular and spatial profiling of immune cells.
• Mapping of cellular interactions.

Speaker:
Assaf Magen
Computational Biologist
Precision Immunology Institute at Mount Sinai

Learn about differences between traditional high-speed cell sorters and gentler microfluidics-based cell sorters. We will review the operational differences and how fast cell sorting is not the best choice for some applications, such as nucleic sorting, gentle cell deposition for cell line development, high-viability cell sorting for downstream applications–and the reasoning behind it. 

We will highlight:

• Concerns with traditional high-pressure cell sorting and why it may not be the best choice for your sensitive cells applications
• How gentle cell deposition improves clonal outgrowth for developing cell lines
• The benefits of low-pressure sorting of highly viable cells or free nuclei to optimize downstream genomics and sequencing applications

Speaker:
Mandana Farhadi
Sr. Product Manager, NanoCellect Biomedical

Applied Cells novel MARS®  platforms provide innovative solutions for Rare Cell isolation.
 
Join us for a webinar introducing MARS® technology and its use examples. Our Guest Elizabeth M. Chislock, Ph.D., is a Senior Research Investigator in the laboratory of Dr. Lewis Chodosh in the Department of Cancer Biology at the University of Pennsylvania. 
 
Dr. Chislock’s primary research interest is in investigating the biology of disseminated tumor cells (DTCs) in the bone marrow in order to better understand the mechanisms underlying breast cancer dormancy and recurrence, including the application of novel pre-enrichment methodologies for improved detection and isolation of these rare tumor cells.

Speaker:
Elizabeth M. Chislock, Ph.D.
University of Pennsylvania

We invite you to join our upcoming webinar with Genetic Engineering & Biotechnology News on October 13th! Dr. Paul Greer from UMass Chan Medical School will present "Spatial Transcriptomics Helps Sniff Out a More Comprehensive Olfactory Map." Dr. Greer will share how his laboratory uses spatial transcriptomics and machine learning to reconstruct a map of the majority of glomerular positions within the mouse olfactory bulb.

A live Q&A session will follow the presentation, offering you a chance to pose questions to our expert panelist.

Speaker:
Paul Greer, PhD
Assistant Professor
UMass Medical School

Since 1959, ILMAC has been the sole Swiss industry fair for chemicals and life sciences that depicts all the industrial applications in process and laboratory technology. As a user-oriented trade fair, ILMAC is geared to experts in pharmaceuticals, chemicals, biotechnology, food, drinks, cosmetics and others.

Get your free ticket by using the following PrioCode: bucher-ilmac22

Data. AI. Precision. Innovation.
For Pharma, Healthcare & Partners

BioTechX is Europe’s largest congress covering diagnostics, precision medicine and digital transformation in pharmaceutical development and healthcare.

BioTechX successfully brings together an amalgamation of genomics, translational medicine, data scientists, IT, bioinformaticians, cheminformaticians, clinicians, healthcare and pharma companies. The event will showcase innovation, demonstrate success and break through the obstacles and barriers to ensure that the innovations in genomics and big data, enter the clinic with speed and efficiency.

This conference will strengthen and consolidate the ties among the cytometry community across Switzerland as we see this conference as the perfect opportunity to discuss ideas and science, interact and socialize. We also hope the program we have put together will raise interest and stimulate discussions among the delegates.

Visit us at our booth! We will be happy to discuss your specific applications!

“Life on Earth: coping with challenges”

It is our pleasure to invite you to the LS2 Annual Meeting 2023 on the topic ““Life on Earth: coping with challenges”", held on 16. / 17. February 2023, together with the Young Scientists' Satellite on 15. February, 2023 in Zurich, at campus Irchel of the University of Zurich.

The LS2 Annual Meeting brings together scientists from all nations and backgrounds to explore the large spectrum united under the umbrella of Life Sciences.