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Logos Biosystems Inc.

DeepLabel™ Antibody Staining Kit for Cleared Tissues

DeepLabel™ Antibody Staining Kit enhances antibody penetration into large clarified tissues for vibrant fluorescence 3D imaging.

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Antibody Labeling for Cleared Tissues

Clearing methods allow light to penetrate samples for imaging, although the method used can affect tissue permeability to molecular probes. Conventional labeling protocols involve the slow diffusion of probes into thin sample sections, which translates to a time-consuming impracticality when applied to thicker samples. The slow progression of diffusion can also lead to uneven staining, with higher, nonspecific binding on the outside of a thicker sample. The new DeepLabel™ Antibody Staining Kit from Logos Biosystems overcomes these obstacles. Optimized for thick, cleared tissues, DeepLabel™ increases tissue permeability and enhances antigen-antibody binding so that antibody labeling of cleared tissues can happen rapidly and efficiently.

DeepLabel™ Antibody Staining Kit

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DeepLabel™ Antibody Staining Kit is a set of non-toxic, ready-to-use reagents optimized for use with clarified tissues for effective antibody penetration and site-specific binding. With DeepLabel™, macromolecular probes rapidly and efficiently penetrate thick, protein-dense tissues at lower antibody concentrations. DeepLabel™ facilitates homogenous antibody staining with 2.6 X greater signal-to-background than conventional staining methods. DeepLabel™ is compatible with virtually all antibodies and all cleared tissues (compatible with CLARITY, PACT, iDISCO, CUBIC, etc).

  • Compatible with multiple clearing methods
  • Simple protocol
  • Vibrant imaging at subcellular resolution
  • Site-specific labeling
  • Homogenous antibody distribution
  • 2.6 X greater signal-to-background
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The X-Clarity™ Tissue Clearing System

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The X-CLARITY™ is a collection of systems and ready-to-use reagents developed by Logos Biosystems to make electrophoretic tissue clearing simple, rapid, and efficient.

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DeepLabel™ Antibody Staining Kit for Cleared Tissues

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