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Applied Cells Inc.

MARS® - Break-through Cell Separation Universal Platform

The MARS® System - Multiphysics Automated Reconfigurable Separation System - is the “one-stop” modular solution for complete cell isolation from complex samples. MARS’s novel design uses active-microfluidic acoustics AND magnetic separation technologies to isolate target cells from whole blood, apheresis, and bone marrow samples. 

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MARS Features

From rare cells to T-cells, the MARS system can isolate target cells with high recovery, high purity, and high throughput (3H Solutions). The system's unique multi-physics approach provides enabling research and cost-effective clinical solutions to the field of Genomics, Tumor Biology, and Cell Therapy with full automation for every lab.

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  • MULTI-PHYSICS
    Multiple physics processes are integrated into state-of-the-art MARS system, to isolate and enrich target cells from biological samples in ways that are not available in today's market.
  • MODULAR SYSTEM
    MARS is designed to be modular, with its basic functions realized in a series of functional modules, enabling an extraordinary capability to meet every user's unique cell separation and sample preparation need, and allowing customization in both the overall work flow and each individual processing step.
  • AUTOMATION
    MARS operation is as simple as (1) loading the sample, (2) pressing the start button, and (3) done - in minutes, making it suitable for SOP of sample preparation in clinical tests, and SOP of cell manufacturing in cell therapies.

MARS EXCELS

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  • Speed
    MARS sample processing speed exceeds existing flow-through cell separation technologies by offering "milliliter per minute" throughput.
  • Performance
    Cells in blood or tissue samples are separated and extracted with high purity, close to zero loss, and alive, enabling countless down-stream cellular and genomics analysis, and meeting cell therapy needs.
  • Simplicity
    MARS operates at the touch of a finger. Target cells within a complex sample are separated, purified and enriched by an automated standardized process, without using a centrifuge and without needing human intervention.
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Multimedia

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News & Events

News

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Applied Cells, Inc.

Pleased to Announce Winning the Annual CYTO 2020 Technology Innovation Showcase

We are pleased to announce that Applied Cells has won the CYTO 2020 Technology Innovation Award at Virtual CYTO, 2020. ISAC, the International Society for the Advancement of Cytometry, held its annual CYTO meeting August 4-5, 2020.

Please also check the CYTO 2020 reference page at www.appliedcells.com/CYTO.

Read More

Events

Applied Cells Webinar on

A Multiphysics Approach for Complete Cell Preparation and Isolation Supporting Tumor Biology, Immunotherapeutics Development and Genetic Testing

Please join Dr. Gregory Schneider and Nicholas Wilson as they show new data on how you can quickly and gently:

  • Wash and concentrate WBCs from whole blood in < 11 minutes with 98% viability without Ficoll or centrifugation
  • Isolate rare cells (CTCs, DTCs, etc.) 
  • Isolate T cells (or other PBMC subpopulations) 

MARS - Multiphysics Automated Reconfigurable Separation Platform 
The “one-stop” modular solution for complete cell isolation from complex samples. MARS novel modular design uses active-microfluidic acoustics and magnetic separation technologies to isolate targeted cells from whole blood, apheresis, frozen PBMC’s, dissociated tumor cells, and bone marrow samples. From rare cells to T-cells, the MARS system can isolate targeted cells with high recovery, high purity, and high reproducibility (H3).

Resources

Posters

Automated Tumor Infiltrating Lymphocyte (TIL) Enrichment for Improved Single Cell Next Generation Sequencing
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MARS System Enables High Throughput Cell Isolation With High Efficiency and High Recovery
DOWNLOAD

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Applied Cells, Inc.

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Measure mitochondrial respiration and glycolysis as well as ATP production rate of live cells.

Measure mitochondrial respiration, glycolysis, and ATP production in live cells in a 96-well format

Overview of Consumables for XF Analyzers

Simple, Automated, Charge-based DNA and RNA Extraction

LUNA-FX7™ Automated Fluorescence Cell Counter with unmatched cell counting accuracy

The MARS® System is the “one-stop” modular solution for complete cell isolation from complex samples

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Automated high content image acquisition and analysis for drug discovery and cell biology

Multicolor fluorescence imaging to data analysis in one device

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The best value benchtop flow cytometer with high flexibility, enhanced sensitivity and resolution.

Optimized solution for assessing mitochondrial function.

Provides real-time measurements of glycolysis

Measures human (Hu) T cell activation response within several minutes of stimulation

Formulated media based on common culture media DMEM or RPMI, and optimized for use in XF assays.

Analytical method for measuring basal state mitochondrial fuel oxidation in live cells

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Provides validated reagents to measure long chain fatty acid oxidation (FAO)

For in vitro studies of long chain fatty acid oxidation by intact cells.

Permeabilizes intact cells in culture, selectively targeting the cellular plasma membrane.

Seahorse XF Real-Time ATP Rate Assay

A suite of optimized solutions for rapidly measuring cellular substrate oxidation

Robust & accurate measurements of both glycolytic and mitochondrial activities in T cell populations

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