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Applied Cells Inc.

MARS® - Break-through Cell Separation Universal Platform

The MARS® System - Multiphysics Automated Reconfigurable Separation System - is the “one-stop” modular solution for complete cell isolation from complex samples. MARS’s novel design uses active-microfluidic acoustics AND magnetic separation technologies to isolate target cells from whole blood, apheresis, and bone marrow samples. 

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MARS Features

From rare cells to T-cells, the MARS system can isolate target cells with high recovery, high purity, and high throughput (3H Solutions). The system's unique multi-physics approach provides enabling research and cost-effective clinical solutions to the field of Genomics, Tumor Biology, and Cell Therapy with full automation for every lab.

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    Multiple physics processes are integrated into state-of-the-art MARS system, to isolate and enrich target cells from biological samples in ways that are not available in today's market.
    MARS is designed to be modular, with its basic functions realized in a series of functional modules, enabling an extraordinary capability to meet every user's unique cell separation and sample preparation need, and allowing customization in both the overall work flow and each individual processing step.
    MARS operation is as simple as (1) loading the sample, (2) pressing the start button, and (3) done - in minutes, making it suitable for SOP of sample preparation in clinical tests, and SOP of cell manufacturing in cell therapies.


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  • Speed
    MARS sample processing speed exceeds existing flow-through cell separation technologies by offering "milliliter per minute" throughput.
  • Performance
    Cells in blood or tissue samples are separated and extracted with high purity, close to zero loss, and alive, enabling countless down-stream cellular and genomics analysis, and meeting cell therapy needs.
  • Simplicity
    MARS operates at the touch of a finger. Target cells within a complex sample are separated, purified and enriched by an automated standardized process, without using a centrifuge and without needing human intervention.
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News & Events


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Applied Cells, Inc.

Pleased to Announce Winning the Annual CYTO 2020 Technology Innovation Showcase

We are pleased to announce that Applied Cells has won the CYTO 2020 Technology Innovation Award at Virtual CYTO, 2020. ISAC, the International Society for the Advancement of Cytometry, held its annual CYTO meeting August 4-5, 2020.

Please also check the CYTO 2020 reference page at www.appliedcells.com/CYTO.

Read More


Applied Cells Webinar on

A Multiphysics Approach for Complete Cell Preparation and Isolation Supporting Tumor Biology, Immunotherapeutics Development and Genetic Testing

Please join Dr. Gregory Schneider and Nicholas Wilson as they show new data on how you can quickly and gently:

  • Wash and concentrate WBCs from whole blood in < 11 minutes with 98% viability without Ficoll or centrifugation
  • Isolate rare cells (CTCs, DTCs, etc.) 
  • Isolate T cells (or other PBMC subpopulations) 

MARS - Multiphysics Automated Reconfigurable Separation Platform 
The “one-stop” modular solution for complete cell isolation from complex samples. MARS novel modular design uses active-microfluidic acoustics and magnetic separation technologies to isolate targeted cells from whole blood, apheresis, frozen PBMC’s, dissociated tumor cells, and bone marrow samples. From rare cells to T-cells, the MARS system can isolate targeted cells with high recovery, high purity, and high reproducibility (H3).



Automated Tumor Infiltrating Lymphocyte (TIL) Enrichment for Improved Single Cell Next Generation Sequencing
MARS System Enables High Throughput Cell Isolation With High Efficiency and High Recovery


Applied Cells, Inc.

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Measure mitochondrial respiration and glycolysis as well as ATP production rate of live cells.

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The MARS® System is the “one-stop” modular solution for complete cell isolation from complex samples

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